Large - scale , high - density ( up to 512 channels ) recording of local circuits in behaving 1 animals 2 3
نویسندگان
چکیده
Large-scale, high-density (up to 512 channels) recording of local circuits in behaving 1 animals 2 3 Antal Berényi 2, , Zoltán Somogyvári , Anett J. Nagy, Lisa Roux, John Long, 4 Shigeyoshi Fujisawa, Eran Stark, Anthony Leonardo, Timothy D. Harris and György 5 Buzsáki 6 7 The Neuroscience Institute New York University, School of Medicine, New York, 8 NY 10016, USA 9 Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of 10 New Jersey, Newark, NJ 07102 11 MTA-SZTE ‘Momentum’ Oscillatory Neural Networks Research Group, University 12 of Szeged, Department of Physiology, Szeged, H-6720, Hungary 13 Wigner Research Center for Physics of the Hungarian Academy of Sciences 14 Department of Theory, Budapest, H-1121, Hungary 15 Laboratory for Systems Neurophysiology, RIKEN Brain Science Institute, Wako, Saitama, 16 351-0198, Japan 17 Howard Hughes Medical, Institute, Janelia Farm Research Campus, Ashburn, Virginia 18 20147, USA 19 20 Correspondence: 21 György Buzsáki 22 [email protected] 23 NYU Neuroscience Institute, New York University, Langone Medical Center 24 East River Science Park, 450 East 29th Street,9th Floor, 25 New York, NY 10016 26 27 Running Head 28 512 channel neuronal recording in behaving rodents 29 30 Articles in PresS. J Neurophysiol (December 18, 2013). doi:10.1152/jn.00785.2013
منابع مشابه
Large-scale, high-density (up to 512 channels) recording of local circuits in behaving animals.
Monitoring representative fractions of neurons from multiple brain circuits in behaving animals is necessary for understanding neuronal computation. Here, we describe a system that allows high-channel-count recordings from a small volume of neuronal tissue using a lightweight signal multiplexing headstage that permits free behavior of small rodents. The system integrates multishank, high-densit...
متن کاملInnovative Methodology Large-scale, high-density (up to 512 channels) recording of local circuits in behaving animals
Antal Berényi, Zoltán Somogyvári, Anett J. Nagy, Lisa Roux, John D. Long, Shigeyoshi Fujisawa, Eran Stark, Anthony Leonardo, Timothy D. Harris, and György Buzsáki New York University Neuroscience Institute, School of Medicine, New York University, New York, New York; Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, New Jersey; MTA-SZTE “Mome...
متن کاملLarge Scale Multielectrode Recording and Stimulation of Neural Activity
Large circuits of neurons are employed by the brain to encode and process information. How this encoding and processing is done is one of the central questions in neuroscience. Since individual neurons communicate with each other through electrical signals (action potentials), the recording of neural activity with arrays of extracellular electrodes is uniquely suited for the investigation of th...
متن کاملMulti-array silicon probes with integrated optical fibers: light-assisted perturbation and recording of local neural circuits in the behaving animal.
Recordings of large neuronal ensembles and neural stimulation of high spatial and temporal precision are important requisites for studying the real-time dynamics of neural networks. Multiple-shank silicon probes enable large-scale monitoring of individual neurons. Optical stimulation of genetically targeted neurons expressing light-sensitive channels or other fast (milliseconds) actuators offer...
متن کاملLarge-scale neural ensemble recording in the brains of freely behaving mice.
With the availability of sophisticated genetic techniques, the mouse is a valuable mammalian model to study the molecular and cellular basis of cognitive behaviors. However, the small size of mice makes it difficult for a systematic investigation of activity patterns of neural networks in vivo. Here we report the development and construction of a high-density ensemble recording array with up to...
متن کامل